关键信息
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基因名
SLAMF9
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简介
SLAM family member 9 (Slamf9) is a member of the signaling lymphocytic activation molecule family. Slamf9 is a cell surface molecule that lacks the signal transduction motifs found in other family members. Slam9 acts mainly as a plasmacytoid dendritic cell (pDC) receptor and is essential for differentiation, function and maintenance of pDCs, and is also involved in the initiation of inflammation and clearance of bacterial infection. SLAMF9 Protein, Mouse (L224P, HEK293, His) is the recombinant mouse-derived SLAMF9 protein, expressed by HEK293 , with C-6*His labeled tag and L224P mutation.
- 应用
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别名
SLAM family member 9; Slamf9
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种属
Mouse
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表达系统
HEK293
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标签
C-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
BAB26328.1
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表达区间
F18-L230, L224P
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氨基酸序列
FSGDDEDPEEVVGVLQESINLSLEIPSNEEIKHIDWLFQNNIAIVKPGKKGQPAVIMAVDPRYRGRVSISESSYSLHISNLTWEDSGLYNAQVNLKTSESHITKSYHLRVYRRLSKPHITVNSNISEEGVCNISLTCSIERAGMDVTYIWLSSQDSTNTSHEGSVLSTSWRPGDKAPSYTCRVSNPISNISSRRISVGSFCADPGYPEKPSML
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蛋白长度
Partial
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分子量
30-80 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
SLAMF9 (Signaling Lymphocytic Activation Molecule Family Member 9) is a member of the SLAM family of proteins, which are involved in immune regulation and cell signaling. Recent studies have highlighted its critical role in modulating immune responses, particularly in relation to T cell activation and differentiation. Understanding the functional mechanisms of SLAMF9 is crucial, as it has been associated with various diseases, including autoimmune disorders and cancers. Research on recombinant SLAMF9 proteins aims to elucidate their structure and biological function, providing insights into the pathways that govern immune responses. By producing SLAMF9 in a recombinant form, scientists can investigate its interactions with other immune molecules, study its signaling pathways, and explore its potential as a therapeutic target or biomarker. Furthermore, recombinant SLAMF9 can be invaluable in developing diagnostic tools and novel immunotherapies, enhancing our ability to manipulate immune responses for better disease management. The background of this research emphasizes the importance of SLAMF9 in immunology and its promising role in advancing our understanding of immune-related diseases.
