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Rabbit Polyclonal C8orf44 Antibody

  • 中文名: C8orf44抗体
  • 别    名: nan
货号: IPDX02835
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/40-1/200 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 1/5000-1/10000 Human,Mouse,Rat

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参考文献

以下是模拟的关于C8orf44抗体的参考文献示例(实际文献需通过学术数据库检索确认):

1. **文献名称**:*Characterization of C8orf44 Protein Expression in Human Tumors Using a Novel Polyclonal Antibody*

**作者**:Smith J, et al.

**摘要**:本研究开发了一种针对C8orf44蛋白的多克隆抗体,并通过免疫印迹和免疫组织化学验证其特异性。结果显示,C8orf44在多种癌症组织中差异表达,可能与肿瘤进展相关。

2. **文献名称**:*C8orf44 Regulates Autophagy via mTOR Signaling Pathway: Evidence from Antibody-Based Knockdown Studies*

**作者**:Li X, et al.

**摘要**:利用C8orf44抗体进行蛋白定位及表达分析,发现C8orf44通过调控mTOR通路影响细胞自噬,提示其在代谢疾病中的潜在作用。

3. **文献名称**:*A Comprehensive Atlas of C8orf44 Distribution in Mouse Brain Using Immunofluorescence*

**作者**:Garcia R, et al.

**摘要**:通过高特异性C8orf44抗体进行小鼠脑组织免疫荧光染色,揭示了该蛋白在神经元中的区域性表达,为神经系统功能研究提供依据。

4. **文献名称**:*C8orf44 Antibody Validation for Flow Cytometry Applications in Hematopoietic Cells*

**作者**:Chen L, et al.

**摘要**:验证了C8orf44抗体在流式细胞术中的适用性,并发现其在造血干细胞中高表达,可能参与细胞分化调控。

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**注意**:以上为模拟内容,实际研究中请通过 **PubMed**、**Google Scholar** 或 **CiteAb** 等平台检索具体文献,关键词建议:`C8orf44 antibody validation`、`C8orf44 protein function`。部分商业抗体公司(如Abcam、Thermo Fisher)的产品页面也可能提供相关应用文献。

背景信息

The C8orf44 antibody is designed to target the protein encoded by the C8orf44 gene (Chromosome 8 Open Reading Frame 44), a poorly characterized gene located on human chromosome 8. While the precise biological function of C8orf44 remains unclear, studies suggest its potential involvement in cellular processes such as protein trafficking, signal transduction, or transcriptional regulation. The gene is conserved across vertebrates, implying evolutionary significance. C8orf44 antibodies are primarily utilized in research to detect protein expression, localization, and interactions via techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Emerging evidence links dysregulation of C8orf44 to diseases, including certain cancers and neurodevelopmental disorders, though mechanistic insights are limited. Antibody validation often includes specificity tests (e.g., knockout cell lines) to ensure minimal cross-reactivity. Commercial C8orf44 antibodies are typically polyclonal or monoclonal, derived from rabbit or mouse hosts. Researchers emphasize the need for further studies to clarify C8orf44's role in health and disease, positioning these antibodies as critical tools for exploratory studies in molecular biology and translational medicine.

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