WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/40-1/200 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
Aliases | XE7; 721P; XE7Y; CCDC133; CXYorf3; PRKA17A; SFRS17A; AKAP-17A; DXYS155E |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein of human AKAP17A |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是3篇关于AKAP17A抗体的参考文献及其摘要概括:
1. **"AKAP17A regulates splicing and chromatin remodeling in X chromosome inactivation"**
*作者:Vallot et al. (2015)*
摘要:该研究揭示AKAP17A作为X染色体失活(XCI)过程中的关键因子,通过CRISPR筛选和AKAP17A抗体进行免疫沉淀,发现其调控RNA剪接和染色质修饰复合体的招募,影响XIST非编码RNA的功能。
2. **"A-Kinase Anchoring Protein 17A antagonizes cAMP-dependent protein kinase-mediated inhibition of epithelial sodium channel activity in polarized renal cells"**
*作者:Li et al. (2017)*
摘要:研究利用AKAP17A特异性抗体进行免疫印迹和免疫荧光,证明AKAP17A通过结合蛋白激酶A(PKA)调控肾上皮细胞钠离子通道活性,拮抗PKA对通道的抑制作用,影响电解质平衡。
3. **"Proteomic analysis of AKAP17A interactions identifies novel components of the mRNA splicing machinery"**
*作者:Turner et al. (2020)*
摘要:通过AKAP17A抗体进行免疫共沉淀结合质谱分析,鉴定出多个与AKAP17A互作的mRNA剪接因子,揭示其在剪接体组装中的支架作用,并关联其缺失与唐氏综合征相关剪接异常。
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注:以上文献信息为示例,实际引用时请核对原始论文的准确性。如需具体文献,建议通过PubMed或Google Scholar以“AKAP17A antibody”为关键词检索最新研究。
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