| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | CGB4; HH23; LSH-B; LSH-beta |
| WB Predicted band size | 15 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human LHB |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于LHB抗体的3篇示例文献(注：以下为虚构文献，仅用于示例格式)：
1. **文献名称**：Production and Characterization of Monoclonal Antibodies Against Luteinizing Hormone Beta Subunit (LHB)
**作者**：Smith J, et al.
**摘要**：本研究成功制备了针对LHB的单克隆抗体，通过ELISA和Western blot验证其高特异性，并应用于血清LH水平的检测，为生殖内分泌疾病诊断提供工具。
2. **文献名称**：LHB Antibody-Based Immunoassay for Ovarian Function Assessment
**作者**：Lee H, Kim S.
**摘要**：开发了一种基于LHB抗体的化学发光免疫分析法，可灵敏检测女性月经周期中LH波动，为多囊卵巢综合征(PCOS)的早期筛查提供新方法。
3. **文献名称**：Role of Autoantibodies to LHB in Male Infertility
**作者**：Wang Y, et al.
**摘要**：发现部分特发性少精症患者血清中存在LHB自身抗体，动物实验表明此类抗体会干扰睾酮合成通路，提示免疫因素在男性不育中的潜在作用。
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提示：实际研究中建议通过PubMed或Google Scholar检索真实文献(关键词：LHB antibody, LHβ subunit, monoclonal antibody)。
Luteinizing hormone beta-subunit (LHB) antibodies are immunoreagents targeting the beta chain of luteinizing hormone (LH), a glycoprotein critical in reproductive physiology. LH, produced by the anterior pituitary, regulates ovulation in females and testosterone synthesis in males by binding to gonadal receptors. The hormone consists of two subunits: alpha (shared with TSH, FSH, and hCG) and beta (LHB), which confers biological specificity. Antibodies against LHB are pivotal in research and diagnostics to distinguish LH from structurally similar hormones, particularly human chorionic gonadotropin (hCG), which shares an identical alpha subunit.
LHB antibodies are utilized in immunoassays to measure LH levels, aiding in diagnosing infertility, assessing pituitary function, and monitoring reproductive disorders like polycystic ovary syndrome (PCOS) or hypogonadism. They also support research on LH receptor interactions and hormonal dysregulation. However, cross-reactivity with hCG or other glycoprotein hormones remains a challenge, necessitating highly specific epitope-targeted antibodies.
Recent advancements include developing monoclonal LHB antibodies for improved consistency and reduced batch variability. These tools are integral in exploring therapeutic applications, such as fertility treatments or hormone-targeted therapies. Despite progress, standardization of assays and mitigating interference from heterophilic antibodies in clinical samples require ongoing refinement. Overall, LHB antibodies serve as essential biological tools bridging reproductive endocrinology research and clinical diagnostics.
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