| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | Homeobox protein Hox-B5, Homeobox protein H241, Homeobox protein Hox-21, Homeobox protein Mu-1, Hoxb5, Hox-21, Hoxb-5 |
| Entrez GeneID | 15413 |
| WB Predicted band size | 29.5kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Mouse |
| Immunogen | This Mouse Hoxb5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Hoxb5. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于LRRC19抗体的3篇参考文献示例(内容为虚构模拟，实际文献需通过学术数据库验证)：
1. **文献名称**：LRRC19 regulates innate immune responses through TLR signaling
**作者**：Zhang Y, et al.
**摘要**：研究利用LRRC19特异性抗体，发现其在巨噬细胞中通过TLR4信号通路调控炎症因子分泌，证实LRRC19在先天免疫中的关键作用。
2. **文献名称**：Expression profiling of LRRC19 in colorectal cancer using immunohistochemistry
**作者**：Wang L, et al.
**摘要**：通过抗LRRC19抗体的免疫组化分析，发现LRRC19在结直肠癌组织中高表达，且与患者预后不良相关，提示其作为潜在生物标志物的价值。
3. **文献名称**：LRRC19 interacts with viral proteins and modulates antiviral defense
**作者**：Chen H, et al.
**摘要**：利用Co-IP和Western blot(基于LRRC19抗体)，揭示LRRC19与流感病毒NS1蛋白相互作用，抑制宿主抗病毒反应的作用机制。
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建议通过PubMed或Google Scholar搜索关键词“LRRC19 antibody”、“LRRC19 function”获取真实文献。注意关注抗体应用场景(如WB/IHC)及生物学结论。
The LRRC19 (Leucine-Rich Repeat-Containing protein 19) antibody is a tool used to study the function and expression of the LRRC19 protein, a member of the leucine-rich repeat (LRR) superfamily. LRRC19 is a transmembrane protein characterized by multiple LRR motifs, which are involved in protein-protein interactions and cellular signaling. While its biological role remains under investigation, LRRC19 is suggested to participate in innate immune responses, potentially interacting with Toll-like receptor (TLR) pathways or modulating inflammatory signaling. It has been implicated in diseases such as cancer, autoimmune disorders, and infections, though mechanistic insights are limited.
LRRC19 antibodies are primarily utilized in research applications, including Western blotting (WB), immunohistochemistry (IHC), and flow cytometry, to detect protein expression levels and localization in tissues or cell lines. These antibodies help elucidate LRRC19's tissue-specific distribution, such as its reported expression in immune cells, epithelial tissues, and certain tumors. Commercial antibodies are typically validated for specificity using knockout controls or siRNA-mediated protein knockdown. Current studies focus on exploring LRRC19's potential as a biomarker or therapeutic target, particularly in cancers where aberrant expression correlates with disease progression. However, further functional studies are needed to define its precise role in physiology and pathology.
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