| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/20-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | LHX; RAB2 |
| WB Predicted band size | 24 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide of human RAB2A |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于RAB2A抗体的3篇参考文献摘要示例(文献信息为虚构，供参考)：
1. **文献名称**：*RAB2A regulates vesicular transport between the endoplasmic reticulum and Golgi apparatus*
**作者**：Moriyama, K., et al.
**摘要**：通过Western blot和免疫荧光技术，研究证实RAB2A抗体可特异性识别其在哺乳动物细胞中的表达，并揭示RAB2A在高尔基体-内质网囊泡运输中的关键调控作用。
2. **文献名称**：*RAB2A overexpression promotes tumorigenesis in pancreatic cancer*
**作者**：Zhang, L., et al.
**摘要**：利用RAB2A抗体进行免疫组化分析，发现胰腺癌组织中RAB2A蛋白显著高表达，且与患者预后不良相关，提示其可作为潜在治疗靶点。
3. **文献名称**：*RAB2A modulates autophagosome-lysosome fusion in neurodegenerative diseases*
**作者**：Xu, Y., et al.
**摘要**：通过免疫共沉淀和免疫印迹技术，研究证明RAB2A抗体能有效检测其在神经元中的定位，并发现RAB2A通过调控自噬体成熟参与阿尔茨海默病的病理进程。
(注：以上文献及作者为示例性内容，实际引用需查询真实数据库如PubMed并核对原文。)
The RAB2A antibody is a crucial tool for studying the RAB2A protein, a member of the RAS-associated binding (RAB) GTPase family within the RAS superfamily. RAB GTPases are key regulators of intracellular vesicle trafficking, membrane dynamics, and organelle organization. Specifically, RAB2A localizes to the endoplasmic reticulum (ER)-Golgi interface and plays a role in mediating vesicular transport between these compartments, as well as autophagosome formation. It is implicated in diverse cellular processes, including secretion, autophagy, and Golgi homeostasis. Dysregulation of RAB2A has been linked to pathological conditions such as cancer progression, neurodegenerative disorders, and diabetes, making it a potential biomarker or therapeutic target.
The RAB2A antibody enables researchers to detect and quantify RAB2A expression in various biological samples using techniques like Western blotting, immunohistochemistry, and immunofluorescence. It is widely employed to investigate RAB2A’s subcellular localization, interaction partners, and functional mechanisms in both normal and disease contexts. Commercial RAB2A antibodies are typically generated using immunogenic peptides or recombinant protein fragments, with validation in specific applications to ensure specificity. However, users must verify cross-reactivity and optimal experimental conditions due to potential variability between antibody clones. Its utility extends to basic research on membrane trafficking pathways and translational studies exploring RAB2A’s role in disease pathogenesis.
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