关键信息
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基因名
DPYSL3
- 应用
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别名
CRMP4; DRP3; ULIP; Dihydropyrimidinase-related protein 3; Collapsin response mediator protein 4; Unc-33-like phosphoprotein 1
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
Q62188
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表达区间
Met1~Thr218
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分子量
28kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
DPYSL3 (Developmental Plasminogen Activator Protein 3) has gained significant attention in recent years due to its pivotal role in neuronal development and its implications in various neurological disorders. This protein belongs to the collapsin response mediator protein (CRMP) family, which is known to regulate axon guidance and neuronal differentiation during embryonic development. Research has shown that DPYSL3 is crucial for neuronal polarity and plays a vital role in synaptic plasticity, potentially influencing learning and memory processes. Furthermore, alterations in DPYSL3 expression have been associated with neurodegenerative diseases, such as Alzheimer's disease and schizophrenia, highlighting its relevance in neurobiology and mental health. The study of recombinant DPYSL3 protein has opened avenues for understanding its molecular mechanisms and interactions within neuronal networks. By elucidating its structure and function, researchers aim to identify potential therapeutic targets and develop strategies for mitigating the effects of neurological disorders linked to DPYSL3 dysregulation. This research emphasizes the importance of understanding the molecular underpinnings of neuronal function and the potential for DPYSL3 as a biomarker or therapeutic target in neurodevelopmental and neurodegenerative diseases.
