关键信息
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基因名
SLITRK6
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简介
The SLITRK6 protein is a key regulator that coordinates neurite growth, which is critical for normal hearing and vision, affecting neuronal development and intercellular communication. Its importance in sensory function emphasizes its important role in the molecular mechanisms of sensory perception. SLITRK6 Protein, Human (HEK293, His) is the recombinant human-derived SLITRK6 protein, expressed by HEK293 , with C-His labeled tag.
- 应用
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别名
SLIT and NTRK-like protein 6; SLITRK6
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种属
Human
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表达系统
HEK293
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标签
C-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H5Y7
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表达区间
S27-S608
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蛋白长度
Extracellular Domain
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分子量
89 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
SLITRK6 is a member of the SLITRK family of proteins, which are integral in neuronal development and synaptic function. This protein has garnered attention due to its involvement in neural circuitry, particularly in the context of brain development and certain neuropsychiatric disorders. SLITRK6 is thought to play a critical role in the regulation of axon growth and guidance, influencing the formation and maintenance of synaptic connections. Research has indicated that dysregulation of SLITRK6 expression may be linked to various neurological conditions, including autism spectrum disorders and schizophrenia. The study of SLITRK6 recombinant protein is essential for understanding its biological functions and mechanisms at the molecular level. By generating and characterizing the recombinant protein, researchers can investigate its interaction with other proteins, its influence on cellular signaling pathways, and its overall impact on neuronal health and disease. Furthermore, understanding the structure-function relationships of SLITRK6 may pave the way for therapeutic approaches targeting its dysregulation. Overall, the exploration of SLITRK6 serves as a promising direction in neurobiological research, with implications for diagnosing and treating neurodevelopmental and neuropsychiatric disorders.
