关键信息
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基因名
CLEC4K
- 应用
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别名
CD207; Langerin
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UJ71
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表达区间
Pro65~Pro328
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分子量
60kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CLEC4K, a member of the C-type lectin receptor family, has garnered significant attention in immunological research due to its role in pathogen recognition and immune response modulation. Initially identified for its expression in dendritic cells, CLEC4K is known to recognize specific carbohydrate structures on various microorganisms, thereby facilitating their uptake and subsequent activation of the immune system. This receptor is pivotal in the differentiation of immune responses, particularly in the context of infectious diseases and potential therapeutic applications. The ability of CLEC4K to trigger immune signaling pathways highlights its importance in pathogen defense and its potential role in shaping adaptive immunity. Recent studies have explored the structural and functional aspects of CLEC4K, including its ligand specificity and the intracellular signaling mechanisms it engages. Investigating the recombinant forms of CLEC4K offers promising avenues for understanding its interactions with various pathogens and its applications in vaccines and immunotherapy. The ongoing research aims to elucidate the various dimensions of CLEC4K’s function, including its impact on disease outcomes and its role in autoimmune conditions, thus paving the way for novel therapeutic strategies that harness the power of this receptor in enhancing immune responses.
