关键信息
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基因名
TAF2
- 应用
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别名
CIF150; TAF2B; TAFII150; TAF2 RNA Polymerase II; Transcription Initiation Factor TFIID Subunit 2; 150 kDa cofactor of initiator function RNA polymerase II TBP-associated factor B
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6P1X5
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表达区间
Pro918~Asp1199
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分子量
38kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
TAF2 (TATA-binding protein-associated factor 2) is a critical component of the transcriptional machinery in eukaryotic cells, playing a vital role in the formation of the TFIID complex, which is essential for the initiation of RNA polymerase II-mediated transcription. The study of TAF2 and its recombinant protein has gained significance due to its involvement in the regulation of gene expression and its potential implications in various diseases, including cancers. Researchers have focused on understanding the structure and function of TAF2 to elucidate its role in transcriptional regulation and cellular processes. The recombinant production of TAF2 allows scientists to investigate its biochemical properties, protein interactions, and functional mechanisms in detail. Furthermore, TAF2 is thought to participate in chromatin remodeling and the assembly of the transcription pre-initiation complex, making it a key factor in the transcriptional response under various physiological and pathological conditions. By exploring the functional dynamics of TAF2, researchers aim to provide insights into its therapeutic potential and contribution to disease mechanisms, which could lead to novel strategies for modulating gene expression in therapeutic contexts. Overall, the research on TAF2 recombinant protein is crucial for advancing our understanding of transcriptional regulation and its relevance in health and disease.
