关键信息
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基因名
FABP1/L-FABP
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简介
FABP1/L-FABP Protein facilitates cholesterol uptake in hepatocytes via lipoproteins, binding cholesterol, free fatty acids, coenzyme A derivatives, bilirubin, and small molecules within the cytoplasm. It may also participate in intracellular lipid transport processes. FABP1/L-FABP Protein, Mouse (His) is the recombinant mouse-derived FABP1/L-FABP protein, expressed by E. coli , with N-6*His labeled tag.
- 应用
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别名
Fabp1; FabplFatty acid-binding protein; liver; 14 kDa selenium-binding protein; Fatty acid-binding protein 1; Liver-type fatty acid-binding protein; L-FABP
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种属
Mouse
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表达系统
E. coli
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标签
N-6*His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
P12710
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表达区间
M1-I127
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蛋白长度
Full Length
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分子量
15 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
FABP1, also known as liver fatty acid-binding protein (L-FABP), is a member of the fatty acid-binding protein family that plays a critical role in the intracellular transport and metabolism of long-chain fatty acids. Its expression is predominantly found in the liver, where it facilitates lipids' uptake, storage, and utilization. Research on FABP1/L-FABP has gained significance due to its involvement in various metabolic disorders, including obesity, insulin resistance, and fatty liver diseases. Abnormal expressions of L-FABP have been linked to the pathogenesis of these conditions, making it a potential biomarker for metabolic syndromes. Moreover, L-FABP is thought to regulate inflammatory processes and has been associated with the development of atherosclerosis. The recombinant production of FABP1/L-FABP enables researchers to study its structure-function relationships, interactions with fatty acids, and potential therapeutic applications. Characterizing the recombinant protein can provide insights into its biological functions and assist in developing targeted interventions for related diseases. Understanding the mechanisms underlying FABP1's role in lipid metabolism may lead to novel strategies for managing metabolic-related health issues. As such, the study of recombinant FABP1/L-FABP is a rapidly expanding field that holds promise for both basic research and clinical applications in the context of metabolic health.
