Cat: IPD-X38825

Recombinant Mouse PCDHa4 Protein,His

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关键信息

  • 基因名

    PCDHa4

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    CNR1; CRNR1; CNRN1

  • 种属

    Mouse

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O88689

  • 表达区间

    Gln30~Gly217

  • 分子量

    27kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

PCDHa4, a member of the polycystic kidney disease (PKD) family of proteins, has garnered significant attention in recent years due to its potential role in neural development and synaptic function. Research indicates that PCDHa4 may be involved in cell adhesion processes within the nervous system, influencing neuronal connectivity and synaptic stability. Moreover, mutations or dysregulation of PCDHa4 have been associated with various neurological disorders, highlighting its importance in the maintenance of healthy neural tissues. The production of recombinant PCDHa4 protein allows researchers to study its structure-function relationships and interactions with other neural proteins in vitro. This is essential for understanding the mechanisms by which PCDHa4 contributes to neural development and the pathogenesis of related diseases. Investigating the functional characteristics of PCDHa4 through recombinant technology not only enhances our understanding of its biological significance but also opens up new avenues for potential therapeutic interventions targeting neurological disorders linked to its dysfunction. As such, the recombinant PCDHa4 protein is a crucial tool for advancing our knowledge of neuronal biology and developing strategies to combat related health issues.

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