Cat: IPD-X39163

Recombinant Mouse FOXD2 Protein,His & GST

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关键信息

  • 基因名

    FOXD2

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    FKHL17; FREAC9; FOX-D2; Forkhead-related protein FKHL17; Forkhead-related transcription factor 9

  • 种属

    Mouse

  • 表达系统

    E. coli

  • 标签

    N- His & GST

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O35392

  • 表达区间

    Met1~Asp206

  • 分子量

    56kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

FOXD2, a member of the forkhead box (FOX) transcription factor family, plays a crucial role in various biological processes, including development, differentiation, and cellular signaling. Its expression is particularly vital during embryogenesis, especially in the formation and maintenance of specific tissues and organs. Research has implicated FOXD2 in the regulation of neural and developmental pathways, suggesting its potential link to neurodevelopmental disorders and other conditions. The recombinant expression of FOXD2 protein allows for detailed functional studies, enabling researchers to explore its role in transcriptional regulation and gene expression modulation. This is significant for understanding how FOXD2 contributes to developmental anomalies and the molecular mechanisms underpinning its function at a cellular level. Additionally, studying recombinant FOXD2 may unveil therapeutic targets or new strategies for treating related disorders. The increasing interest in FOXD2 stems from its potential as a biomarker and its involvement in complex genetic networks, making it a focal point for investigations into developmental biology and genetics. Understanding FOXD2's precise roles in various pathways enhances our comprehension of its implications in health and disease, providing a foundation for future research and potential clinical applications.

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