关键信息
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基因名
FOXP2
- 应用
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别名
FOX-P2; CAGH44; SPCH1; TNRC10; Trinucleotide Repeat Containing 10; Forkhead/Winged-Helix Transcription Factor; Speech And Language Disorder 1; CAG Repeat Protein 44
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15409
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表达区间
Met1~Ile244
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分子量
58kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
The FOXP2 gene is critically associated with the development of speech and language skills in humans, and its encoded protein, FOXP2, plays a pivotal role in neural processes related to these functions. Research into FOXP2 has garnered considerable attention due to its evolutionary significance; mutations in this gene are linked to speech and language disorders, as evidenced by studies of family members with specific communication impairments. A notable feature of FOXP2 is its evolutionary conservation, with homologs found across various species, suggesting its fundamental role in neural and vocal development. The study of recombinant FOXP2 protein has proven essential for understanding its biochemical properties, functional mechanisms, and interactions with other proteins. By producing recombinant FOXP2 in various expression systems, researchers can investigate its structure and functional dynamics, analyze the impact of specific mutations, and elucidate the pathways involved in communication. This line of research not only enhances our understanding of language evolution but also has potential implications for developing therapeutic strategies for communication disorders. Overall, the exploration of FOXP2 and its recombinant protein form represents a multidisciplinary effort bridging genetics, neuroscience, and linguistics, contributing to our comprehension of the intricate relationship between biology and human phenotype.
