关键信息
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基因名
FUBP1
- 应用
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别名
FBP; FUBP; hDH V; DNA helicase V
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96AE4
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表达区间
Ala2~Asn228
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分子量
30kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
FUBP1 (Far Upstream Element Binding Protein 1) is a key regulatory protein involved in various cellular processes, including mRNA stability, transcriptional regulation, and the cellular response to stress. It is essential for maintaining the expression of several genes linked to cell proliferation and differentiation. Recent studies have highlighted the role of FUBP1 in the development and progression of various cancers, where its overexpression correlates with poor prognosis. Notably, FUBP1 interacts with different cellular pathways, influencing the expression of oncogenes and tumor suppressor genes. Given its crucial involvement in tumor biology, FUBP1 has garnered attention as a potential biomarker and therapeutic target. Research on recombinant FUBP1 protein aims to elucidate its molecular mechanisms in detail, particularly its binding interactions with RNA and other proteins. The generation of recombinant FUBP1 enables detailed structural and functional studies, which are vital for understanding its role in normal physiology and disease states. Moreover, studying the recombinant protein facilitates the exploration of small molecules or peptides that could inhibit its function, potentially leading to novel cancer therapies. Through these investigations, researchers hope to develop better diagnostic tools and therapeutic strategies targeting FUBP1-mediated pathways in cancer and other diseases.
