关键信息
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基因名
MAPRE1
- 应用
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别名
EB1; Adenomatous Polyposis Coli-Binding protein; APC-binding protein EB1; End-binding protein 1
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15691
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表达区间
Ala2~Tyr268
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分子量
34kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MAPRE1 (Microtubule-Associated Protein RE1) is a member of the MAPRE family, which plays a crucial role in microtubule dynamics and cellular processes such as mitosis and intracellular transport. Recent studies have indicated that MAPRE1 is involved in cancer pathology, where its expression levels correlate with tumor progression and patient prognosis. The protein is also linked to various neurodegenerative disorders, suggesting its importance in neuronal integrity and function. Researchers have begun exploring MAPRE1 as a potential therapeutic target due to its pivotal role in microtubule stability and cell proliferation. Furthermore, its interactions with other key proteins, including those involved in signaling pathways and cytoskeletal organization, highlight its significance in maintaining cellular homeostasis. Understanding the structure, function, and regulatory mechanisms of MAPRE1 could provide insights into its potential applications in targeted therapies for cancer and neurodegenerative diseases. Given these implications, the study of MAPRE1 recombinant protein is essential for elucidating its biological functions and therapeutic potential, paving the way for novel intervention strategies in related diseases.
