关键信息
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基因名
PTTG1IP
- 应用
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别名
PBF; C21orf1; C21orf3; Pituitary tumor-transforming gene protein-binding factor
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P53801
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表达区间
Gln33~Glu96
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分子量
37kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
PTTG1IP (PTTG1 interacting protein) is a crucial regulator involved in various cellular processes, particularly those related to cell cycle regulation and cancer biology. It interacts with the securin protein PTTG1, which plays a significant role in mitosis and the prevention of premature sister chromatid separation. Aberrations in PTTG1IP expression have been linked to several cancers, making it a potential biomarker and therapeutic target. Researchers aim to understand the molecular mechanisms by which PTTG1IP modulates cell proliferation and apoptosis, as well as its implications in tumorigenesis. Recombinant PTTG1IP protein production allows scientists to conduct functional assays and structural analyses, which facilitate the study of its interactions with other proteins and its role in cancer progression. Understanding the biological functions and pathways associated with PTTG1IP can lead to novel approaches for cancer treatment, highlighting its significance in oncological studies. Overall, PTTG1IP serves as a promising candidate in the search for effective strategies in cancer therapy, warranting further exploration of its role in cellular dynamics and tumor biology.
