关键信息
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基因名
EN2
- 应用
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别名
AUTS1
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P19622
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表达区间
Met1~Glu333
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分子量
40kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
EN2 (Engrailed 2) is a transcription factor that belongs to the engrailed gene family, which plays a crucial role in the development and patterning of the central nervous system during embryonic development. Research has highlighted its significance in neurodevelopmental diseases and disorders, particularly in autism spectrum disorders (ASD) and schizophrenia, where altered EN2 expression has been associated with aberrant neural connectivity and behavior. The interest in EN2 is further fueled by its potential therapeutic implications, as understanding its functions and mechanisms might contribute to developing targeted interventions for neurodevelopmental conditions. Additionally, EN2's expression patterns and effects on neuronal differentiation have made it a focus of genetic studies aimed at uncovering the molecular pathways involved in brain development. Recombining EN2 proteins in laboratory settings allows researchers to explore their biochemical properties, binding affinities, and interaction with other cellular proteins, providing valuable insights into its role in neurogenesis. Overall, EN2 recombined protein research bridges fundamental biology with potential clinical applications, emphasizing the gene's importance in understanding both normal and pathological brain development.
