关键信息
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基因名
KRT71
- 应用
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别名
KRT6IRS; KRT6IRS1; K6IRS1; CK-71; K71; Cytokeratin-71; Type II inner root sheath-specific keratin-K6irs1; Type-II keratin Kb34; Keratin, type II cytoskeletal 71
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9R0H5
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表达区间
Arg132~Glu440
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分子量
37kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
KRT71, also known as keratin 71, is a member of the keratin family of proteins, primarily expressed in the epithelial tissues of the skin and hair follicles. Research into KRT71 has garnered interest due to its potential roles in various biological processes, including cellular differentiation, structural support, and response to injury. As a key component of the cytoskeleton in epithelial cells, it contributes to the mechanical stability of tissues. Recent studies suggest that mutations or dysregulation of KRT71 may be implicated in certain skin disorders and hair loss conditions, highlighting its significance in dermatological research. Additionally, KRT71 has been investigated for its potential use as a biomarker for skin cancers and other neoplastic conditions. The production of recombinant KRT71 protein allows for detailed studies into its functional properties, interactions with other cellular components, and the pathological consequences of its alteration. This research can pave the way for novel therapeutic strategies targeting skin-related diseases and aid in the development of regenerative medicine approaches. As our understanding of KRT71 expands, it could provide valuable insights into keratinocyte biology and offers potential avenues for clinical applications in dermatology and oncology.
