关键信息
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基因名
Collectrin/TMEM27
- 应用
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别名
NX17; Collectrin
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9ESG4
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表达区间
Glu15~Pro135
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分子量
16kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Collectrin, also known as TMEM27, is a transmembrane protein that plays a crucial role in various physiological processes, particularly in kidney function and glucose homeostasis. Initially discovered for its involvement in the secretion of insulin by pancreatic beta cells, Collectrin has garnered attention due to its implications in metabolic disorders such as obesity and diabetes. Research shows that Collectrin facilitates the proper positioning of glucose transporters and is implicated in the regulation of renal ion balance, making it vital for maintaining homeostasis. Recent studies have explored its potential role as a biomarker for kidney injury and as a therapeutic target for metabolic diseases. The recombinant form of Collectrin/TMEM27 allows for in-depth characterization of its structural and functional properties, enabling scientists to dissect its mechanisms of action and interactions with other proteins within cellular pathways. Thus, understanding the biology of Collectrin not only enhances our knowledge of metabolic regulation but also offers promising avenues for developing interventions for related disorders.
