关键信息
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基因名
DYRK2
- 应用
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别名
/
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种属
Human
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表达系统
Baculovirus
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q92630-2
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表达区间
1-528aa
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分子量
61.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
DYRK2 (Dual-specificity tyrosine phosphorylation-regulated kinase 2) is a member of the DYRK family of kinases, which play significant roles in various cellular processes, including cell proliferation, differentiation, and apoptosis. The interest in DYRK2 has surged due to its involvement in several critical biological pathways and its potential implications in cancer and neurodegenerative diseases. Research has shown that DYRK2 can modulate the phosphorylation states of several key substrates, influencing cellular signaling networks. Additionally, DYRK2 is recognized for its regulatory functions in the cell cycle and its role in the response to cellular stress. The burgeoning understanding of DYRK2's mechanisms has paved the way for investigating its potential as a therapeutic target. Notably, the development of recombinant DYRK2 protein presents an opportunity to explore its biochemical properties, interactions, and kinase activity in greater detail. Such studies are essential for elucidating the role of DYRK2 in pathological conditions and can lead to the identification of novel drug candidates that specifically inhibit or activate this kinase. The growing body of evidence surrounding DYRK2 underscores the significance of understanding its functional dynamics through advanced molecular techniques, fostering advancements in targeted therapies and personalized medicine.
