关键信息
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基因名
CSE1L
- 应用
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别名
Cellular apoptosis susceptibility protein Chromosome segregation 1-like protein Importin-alpha re-exporter
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P55060
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表达区间
1-200aa
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分子量
39.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CSE1L, or Chromosome Segregation 1-Like, is a protein that plays a vital role in cellular processes, particularly in the regulation of nucleocytoplasmic transport and cell cycle progression. Research into CSE1L has garnered attention due to its implications in various biological processes, including cell division and the maintenance of genomic stability. Studies have shown that CSE1L is involved in the transport of essential proteins and RNA molecules between the nucleus and the cytoplasm, a function crucial for cellular function and homeostasis. Aberrations in CSE1L expression or function have been linked to several diseases, including cancer, wherein altered nucleocytoplasmic transport can lead to the mismanagement of oncoproteins and tumor suppressors. Understanding the structure and function of CSE1L through recombinant protein studies is significant for elucidating its mechanisms in cellular biology and its potential as a therapeutic target. Continued research on CSE1L not only aims to uncover its role in fundamental cellular processes but also seeks to explore its relevance in disease contexts, opening avenues for targeted drug development that could mitigate the effects of its dysregulation.
