关键信息
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基因名
IGSF11
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简介
IGSF11 (Immunoglobulin superfamily member 11) operates as a cell adhesion molecule by engaging in homophilic interactions, thereby facilitating cell-to-cell adhesion. Additionally, IGSF11 is implicated in the stimulation of cell growth, suggesting a role in cellular proliferation and potentially contributing to regulatory pathways involved in cellular development and maintenance. IGSF11 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGSF11 protein, expressed by HEK293 , with C-His labeled tag.
- 应用
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生物活性
VISTA immobilized on CM5 Chip can bind IGSF11 with an affinity constant of 160.8 μM as determined in SPR assay. VISTA immobilized on CM5 Chip can bind IGSF11 with an affinity constant of 160.8 μM as determined in SPR assay.
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别名
IgSF11; Bt-IGSF; Bt IGSF; BtIGSF; VSIG3; CXADRL1; CT119
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种属
Mouse
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表达系统
HEK293
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标签
C-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
P0C673
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表达区间
L23-V240
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蛋白长度
Extracellular Domain
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分子量
32-42 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
IGSF11 (Immunoglobulin Superfamily Member 11) is a member of the immunoglobulin superfamily known for its role in cellular adhesion and signaling processes. Initial research indicated that IGSF11 is predominantly expressed in immune tissues, suggesting its potential involvement in immune responses and cell-to-cell interactions. Recent studies have identified its significance in various biological processes, including the regulation of T-cell activation and differentiation, pointing to its potential role in autoimmune diseases and cancer. The generation of recombinant IGSF11 protein has become a focal point in research to elucidate its functional properties and interactions. By producing IGSF11 in a recombinant form, researchers can investigate its structure-function relationships, binding affinities, and how it influences immune cell behavior. This research may lead to a deeper understanding of IGSF11’s contributions to immune regulation and its implications in pathological conditions. Furthermore, recombinant IGSF11 could serve as a tool for therapeutic interventions or as a biomarker for specific diseases. As the field of immunology continues to advance, the study of recombinant IGSF11 protein stands to offer valuable insights into its potential roles in health and disease.
