关键信息
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基因名
GNRHR2
- 应用
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别名
Type II GnRH receptor
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种属
Rhesus Macaque
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q95JG1
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表达区间
1-379aa
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分子量
44.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
GNRHR2, or Gonadotropin-Releasing Hormone Receptor 2, is a crucial member of the GNRH receptor family, which plays a pivotal role in the regulation of reproductive hormone release and overall reproductive function. This receptor binds to gonadotropin-releasing hormone (GnRH) and mediates the downstream signaling that influences gonadotropin secretion from the anterior pituitary, thus orchestrating the reproductive axis. Research into GNRHR2 has gained attention due to its potential implications in various reproductive disorders, including hypogonadism, infertility, and certain endocrine cancers. The recombinant expression of GNRHR2 protein facilitates a deeper understanding of its structure, function, and interaction with GnRH. By studying the receptor in a controlled laboratory environment, scientists can explore its pharmacological properties, assess the impact of mutations, and develop targeted therapies that could restore normal reproductive function. Furthermore, the design of GNRHR2 agonists or antagonists holds promise for clinical applications in treating reproductive health issues and understanding the broader implications of GnRH signaling in cancer biology. Consequently, research on GNRHR2 recombinant proteins is not only essential for elucidating the basic biology of reproductive endocrinology but also represents a critical step towards advancing therapeutic strategies for various related disorders.
