Cat: IPD-X39831

Recombinant Human GNRH2 Protein ,His & SUMO

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关键信息

  • 基因名

    GNRH2

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Progonadoliberin II

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N- His-SUMO

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O43555

  • 表达区间

    24-120aa

  • 分子量

    26.5 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

Gonadotropin-releasing hormone 2 (GnRH2) is a pivotal peptide hormone involved in the regulation of reproductive functions across various vertebrate species. Initially discovered in fish, GnRH2 is known to play a critical role in stimulating the release of gonadotropins from the anterior pituitary gland, thus influencing gonadal development, sexual maturation, and reproductive cycles. The interest in recombinant GnRH2 protein has increased due to its potential applications in reproductive biology and endocrinology. Research has shown that GnRH2 is distinct from the more widely studied GnRH1, exhibiting unique structural and functional properties. The recombinant production of GnRH2 enables scientists to investigate its physiological roles, interactions with GnRH receptors, and potential therapeutic applications in treating reproductive disorders. Moreover, understanding GnRH2's mechanism can provide insights into evolutionary adaptations of reproductive strategies among vertebrates. Advances in molecular biology and biotechnology have facilitated the expression and purification of GnRH2, paving the way for in vitro studies and possible clinical applications. Consequently, GnRH2 research holds promise for enhancing our knowledge of reproductive health and developing novel strategies for managing related conditions.

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