Cat: IPD-X41217

Recombinant Leishmania infantum JBP1 Protein ,His

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关键信息

  • 基因名

    JBP1

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    J-binding protein 1;Thymidine hydroxylase JBP1

  • 种属

    Leishmania infantum

  • 表达系统

    E. coli

  • 标签

    N- His-V5

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    A4HU70

  • 表达区间

    200-600aa

  • 分子量

    53.4 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

JBP1, or JunB-binding protein 1, is a relatively novel protein that has garnered attention in the field of molecular biology and biomedicine due to its potential roles in cellular processes and disease mechanisms. Research indicates that JBP1 may be involved in various signaling pathways that regulate cell proliferation, apoptosis, and differentiation, particularly in the context of cancer and immune responses. Its interaction with JunB, a transcription factor that plays a critical role in gene expression, suggests that JBP1 may influence transcriptional regulation, thereby impacting oncogenic processes. Furthermore, studies have linked JBP1 to inflammatory responses, highlighting its potential as a therapeutic target in inflammatory diseases. The recombinant production of JBP1 presents a significant opportunity to delve deeper into its functional roles and interactions, enabling researchers to elucidate its mechanistic pathways and evaluate its potential as a biomarker for disease. Through advanced techniques in protein expression and purification, the study of JBP1 can facilitate the development of novel therapeutic strategies and contribute to a better understanding of its implications in various pathologies. As research progresses, the elucidation of the precise biological functions of JBP1 will pave the way for its application in clinical contexts, emphasizing the necessity for continued exploration of this intriguing protein.

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