关键信息
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基因名
ARL14
- 应用
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别名
ARL14；ARF7；ADP-ribosylation factor-like Protein 14
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BZQ6
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表达区间
1-192aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSLGSKNPQ TKQAQVLLLG LDSAGKSTLL YKLKLAKDIT TIPTIGFNVE MIELERNLSL TVWDVGGQEK MRTVWGCYCE NTDGLVYVVD STDKQRLEES QRQFEHILKN EHIKNVPVVL LANKQDMPGA LTAEDITRMF KVKKLCSDRN WYVQPCCALT GEGLAQGFRK LTGFVKSHMK SRGDTLAFFK QN
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分子量
24 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
The ARL14 protein, a member of the Arf (ADP-ribosylation factor) family, plays a crucial role in cellular processes such as membrane trafficking, cytoskeletal dynamics, and signal transduction. Recent studies have highlighted its involvement in regulating the actin cytoskeleton and maintaining cell shape, which is essential for various cellular functions and processes including migration, division, and differentiation. Dysregulation of ARL14 has been linked to various diseases, including cancer and neurodegenerative disorders, making it a potential target for therapeutic interventions. Given the increasing interest in the molecular mechanisms behind cell behavior, researchers have focused on generating recombinant ARL14 proteins to study their biochemical properties, interactions with other proteins, and roles in cellular pathways. This research not only aims to elucidate the specific functions of ARL14 in health and disease but also seeks to develop novel strategies for manipulating its activity, which could have significant implications for biomedical applications. By employing techniques such as biochemistry, cell biology, and structural biology, scientists are working towards a comprehensive understanding of ARL14's molecular mechanisms and its impact on cellular homeostasis.
