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Rabbit Polyclonal MBOAT2 Antibody

  • 中文名： MBOAT2抗体
  • 别    名： Lysophospholipid acyltransferase 2, LPLAT 2, 231-, 1-acylglycerophosphate O-acyltransferase, 1-acylglycerophosphoethanolamine O-acyltransferase, 231n7, Lysophosphatidic acid acyltransferase, LPAAT, Lyso-PA acyltransferase, Lysophosphatidylethanolamine acy
货号: IPDX31866
Price： ￥1180
数量：
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验证与应用

应用及物种
WB 1/1000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesLysophospholipid acyltransferase 2, LPLAT 2, 231-, 1-acylglycerophosphate O-acyltransferase, 1-acylglycerophosphoethanolamine O-acyltransferase, 231n7, Lysophosphatidic acid acyltransferase, LPAAT, Lyso-PA acyltransferase, Lysophosphatidylethanolamine acyltransferase, LPEAT, Lyso-PE acyltransferase, Membrane-bound O-acyltransferase domain-containing protein 2, O-acyltransferase domain-containing protein 2, MBOAT2, OACT2
Entrez GeneID129642
WB Predicted band size59.5kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenThis MBOAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the Central region of human MBOAT2.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

以下是关于MBOAT2抗体的3篇示例参考文献(注：以下为虚构示例，仅作格式参考)：

1. **"MBOAT2 Antibody Validation in Lipid Metabolism Studies"**

*作者：Zhang et al. (2022)*

摘要：本研究验证了一种新型MBOAT2抗体的特异性，通过Western blot和免疫组化证实其在人肝组织中的表达模式，并发现MBOAT2与甘油三酯代谢调控相关。

2. **"Role of MBOAT2 in Neuronal Membrane Remodeling"**

*作者：Lee et al. (2021)*

摘要：利用MBOAT2抗体进行免疫荧光染色，揭示其在小鼠神经元突触膜中的定位，表明MBOAT2可能参与神经发育过程中的磷脂酰肌醇修饰。

3. **"MBOAT2 as a Biomarker in Colorectal Cancer"**

*作者：Smith et al. (2020)*

摘要：通过MBOAT2抗体检测肿瘤组织样本，发现其表达水平与结直肠癌患者生存率显著相关，提示其作为潜在治疗靶点的可能性。

(注：实际文献需通过PubMed/Google Scholar等平台以“MBOAT2 antibody”为关键词检索。)

背景信息

The MBOAT2 (membrane-bound O-acyltransferase domain-containing protein 2) antibody is a tool used to study the function and expression of the MBOAT2 enzyme, which belongs to a conserved family of membrane-bound O-acyltransferases involved in lipid metabolism. MBOAT2 is implicated in acyltransferase activity, potentially modifying lipids or proteins by transferring acyl groups, though its precise substrates and biological roles remain less characterized compared to other family members like DGAT1 or ACAT1. Research suggests MBOAT2 may influence lipid homeostasis, membrane remodeling, or signaling pathways. The antibody, typically developed in hosts such as rabbits or mice, targets specific epitopes of human or model organism MBOAT2. enabling applications like Western blotting, immunofluorescence, and immunohistochemistry to localize the protein in tissues or cultured cells. Validation often includes knockout controls, siRNA knockdown, or tagged protein overexpression to confirm specificity. Studies using MBOAT2 antibodies aim to elucidate its role in physiological processes, such as lipid droplet formation or organelle membrane dynamics, and its potential links to metabolic disorders, neurodegenerative diseases, or cancer. Commercial antibodies vary in clonality, immunogen design, and cross-reactivity across species, requiring careful selection based on experimental needs. Ongoing research with these reagents seeks to clarify MBOAT2's enzymatic mechanisms and therapeutic relevance.

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