关键信息
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基因名
MAST2
- 应用
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别名
MAST2；KIAA0807；MAST205；Microtubule-associated serine/threonine-Protein kinase 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6P0Q8
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表达区间
全长
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氨基酸序列
full
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MAST2 (Microtubule-associated protein/MAP-tau) is a member of the MAST (microtubule associated serine/threonine kinase) family, which plays a crucial role in microtubule dynamics and cellular signaling pathways. Research into MAST2 has gained prominence due to its involvement in various cellular processes, including cell cycle regulation, neuronal development, and response to stress. Abnormal expression or dysfunction of MAST2 has been linked to several neurodegenerative diseases, including Alzheimer's disease and tauopathies, where tau protein hyperphosphorylation leads to neurofibrillary tangles. Additionally, MAST2 has been implicated in cancer progression through its effects on cytoskeletal organization and cellular motility. As a result, the study of MAST2 recombinant protein has potential implications for therapeutic interventions targeting these diseases. By understanding the molecular mechanisms by which MAST2 operates, researchers aim to elucidate its precise role in cellular functions and develop novel strategies for disease management. The recombinant production of MAST2 allows for the detailed study of its biochemical properties, protein interactions, and phosphorylation states, which are vital for deciphering its roles in health and disease. Through these investigations, MAST2 emerges as a promising candidate for further exploration in both basic and translational research, highlighting the need for continued focus on this multifaceted protein in the context of neurobiology and oncology.
