关键信息
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基因名
NRG3
- 应用
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别名
NRG3；Pro-neuregulin-3. membrane-bound isoform
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P56975
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表达区间
282-342aa
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氨基酸序列
ERSEHFKPCR DKDLAYCLND GECFVIETLT GSHKHCRCKE GYQGVRCDQF LPKTDSILSD P
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分子量
34 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
NRG3 (Neuregulin-3) is a member of the Neuregulin family of growth factors, which have been implicated in various neurodevelopmental processes and the function of the nervous system. Research surrounding NRG3 has gained momentum due to its potential role in synaptic modulation, neuronal survival, and myelination. It is particularly relevant in the context of psychiatric disorders such as schizophrenia, where genetic variations in the NRG3 gene have been associated with increased risk. Recent studies have focused on the functions of NRG3 in the central nervous system, including its influence on synaptic plasticity and cognitive functions. The study of NRG3 recombinant protein is crucial for understanding its biological mechanisms and interactions with other signaling pathways. By producing and characterizing NRG3 in vitro, researchers aim to elucidate its roles in synaptic development and maintenance, as well as its therapeutic potential in neurodegenerative diseases and mental health disorders. The investigation into NRG3 also presents opportunities for developing targeted therapies that could modulate its signaling for clinical benefits. Overall, the growing body of evidence underscores the importance of NRG3 in neurobiology and its promise as a target for future research and therapeutic interventions.
