关键信息
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基因名
Gng12
- 应用
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别名
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
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种属
Mouse
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9DAS9
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表达区间
2-69aa
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分子量
15.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Gng12 is a gene that encodes a protein belonging to the G-protein gamma subunit family, which is critical in various cellular signaling pathways. Research on Gng12 has gained attention due to its involvement in modulating the function of G-protein coupled receptors (GPCRs), which are key players in numerous physiological processes and pathophysiological conditions. The understanding of Gng12's role in signal transduction is crucial for elucidating mechanisms underlying diseases such as cancer, cardiovascular disorders, and neurological conditions. Furthermore, as a potential therapeutic target, Gng12 could pave the way for the development of novel drugs aimed at treating diseases associated with dysfunctional GPCR signaling. In recent years, advances in recombinant DNA technology have facilitated the production of Gng12 recombinant proteins, thus enabling detailed studies of its structure and function. Researchers are investigating the interactions between Gng12 and other G-protein subunits to better understand its specific roles and regulatory mechanisms in cellular processes. Such studies could ultimately contribute to the identification of new biomarkers for disease and the formulation of innovative therapeutic strategies. Through this research, Gng12 is emerging as an important molecule in the field of molecular biology and pharmacology, highlighting the need for continued exploration of its biological significance.
