关键信息
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基因名
CXCL4
- 应用
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别名
CXCL4；CXCL4；SCYB4；;Platelet factor 4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P02776
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表达区间
32-101aa
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氨基酸序列
EAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRK ICLDLQAPLYKKIIKKLLES
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分子量
78 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CXCL4, also known as platelet factor 4 (PF4), is a CXC chemokine that plays a crucial role in various physiological and pathological processes, including inflammation, angiogenesis, and hematopoiesis. It is primarily secreted by activated platelets and is involved in the recruitment of immune cells to sites of injury or infection. Due to its multifaceted roles, CXCL4 has garnered significant interest in research related to cardiovascular diseases, cancer, and autoimmune disorders. The study of recombinant CXCL4 protein has been pivotal in understanding its structure-function relationships, interaction with receptors, and potential therapeutic applications. Recombinant forms of CXCL4 can be produced in various expression systems, allowing researchers to investigate its biological activities and develop potential therapeutic strategies. For instance, recent studies have highlighted CXCL4's ability to modulate immune responses and inhibit tumor growth, suggesting its promise as a novel biomarker or therapeutic agent. As research progresses, the recombinant CXCL4 protein is being evaluated in preclinical models and clinical trials, paving the way for new insights into its role in human health and disease. Overall, CXCL4 represents a fascinating subject of study within the field of chemokine research, with implications for targeted therapies in inflammatory and neoplastic conditions.
