关键信息
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基因名
GPR107
- 应用
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别名
(Lung seven transmembrane receptor 1)
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种属
Human
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5VW38
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表达区间
40-263aa
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分子量
32.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
GPR107 is an orphan G protein-coupled receptor (GPCR) that has garnered interest in recent years due to its potential roles in various physiological processes and disease states. As a member of the GPCR superfamily, GPR107 is characterized by its unique structure, which includes seven transmembrane domains, a hallmark of GPCRs that facilitates signal transduction across cell membranes. The receptor is known to be involved in cellular responses to ligands, but its exact physiological function remains largely elusive, leading to a growing demand for research to elucidate its role in human health and disease. Emerging studies suggest that GPR107 may play a part in tumor biology, neurobiology, and metabolic processes, making it a candidate for therapeutic targeting in a range of conditions such as cancer and neurodegenerative diseases. Given the complexity of GPCR signaling and the potential implications of GPR107 in pathological conditions, the production of recombinant GPR107 protein is essential for functional assays, structural studies, and drug discovery efforts. Understanding the receptor's ligand-binding properties and downstream signaling pathways through the use of its recombinant form will enhance our knowledge of GPR107's role in cellular communication and open new avenues for developing targeted therapies. Advances in recombinant protein technology enable the generation of purified GPR107 for high-throughput screening and structural analysis, ultimately contributing to the broader field of GPCR research and personalized medicine.
