关键信息
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基因名
TOR1B
- 应用
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别名
TOR1B；DQ1；Torsin-1B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O14657
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表达区间
25-336aa
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氨基酸序列
FEPITV GLAIGAASAI TGYLSYNDIY CRFAECCREE RPLNASALKL DLEEKLFGQH LATEVIFKAL TGFRNNKNPK KPLTLSLHGW AGTGKNFVSQ IVAENLHPKG LKSNFVHLFV STLHFPHEQK IKLYQDQLQK WIRGNVSACA NSVFIFDEMD KLHPGIIDAI KPFLDYYEQV DGVSYRKAIF IFLSNAGGDL ITKTALDFWR AGRKREDIQL KDLEPVLSVG VFNNKHSGLW HSGLIDKNLI DYFIPFLPLE YRHVKMCVRA EMRARGSAID EDIVTRVAEE MTFFPRDEKI YSDKGCKTVQ SRLDFH
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
TOR1B is a member of the Target of Rapamycin (TOR) signaling pathway, which plays a crucial role in regulating cell growth, proliferation, and metabolism in response to nutrient availability and environmental cues. Research on TOR1B, particularly its role in various biological processes and diseases, has gained significant attention in recent years. This protein is associated with cellular responses to stress, aging, and cancer. The TOR signaling pathway has been identified as a critical regulator of autophagy and protein synthesis, impacting stem cell biology and tissue homeostasis. Understanding the function and regulation of TOR1B could reveal potential therapeutic targets for diseases linked to dysregulation of this pathway, such as cancer and metabolic disorders. Advances in recombinant protein technology have enabled researchers to produce and study TOR1B in detail, allowing for in-depth analysis of its structure, function, and interactions with other proteins. This knowledge is vital for elucidating the mechanisms behind TOR1B's involvement in various cellular processes and its potential as a biomarker or therapeutic target in conditions related to aberrant TOR signaling.
