关键信息
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基因名
CSPG5
- 应用
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别名
CSPG5；CALEB；NGC；Chondroitin sulfate proteoglycan 5
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95196
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表达区间
1-566aa
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氨基酸序列
MGRAGGGGPGRGPPPLLLFLGAALVLASGAVPAREAGSAVEAEELVKGSPAWEPPANDTREEAGPPAAGEDEASWTAPGGELAGPEEVLQESAAVTGTAWLEADSPGLGGVTAEAGSGDAQALPATLQAPHEVLGQSIMPPAIPEATEASGPPSPTPGDKLSPASELPKESPLEVWLNLGGSTPDPQGPELTYPFQGTLEPQPASDIIDIDYFEGLDGEGRGADLGSFPGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLDEEEEEEEDDKDAVGGGDLEDENELLVPTGKPGLGPGTGQPTSRWHAVPPQHTLGSVPGSSIALRPRPGEPGRDLASSENGTECRSGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTNKFRTPSELHNDNFSLSTIAEGSHPNVRKLCNTPRTSSPHARALAHYDNVICQDDPSAPHKIQEVLKSCLKEEESFNIQNSMSPKLEGGKGDQADLDVNCLQNNLT
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分子量
60 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CSPG5, or chondroitin sulfate proteoglycan 5, is a member of the CSPG family, which plays a critical role in various biological processes, including cell adhesion, migration, and proliferation. It is predominantly expressed in the central nervous system and has been implicated in the development and progression of several tumors. Its abnormal expression has been associated with aggressive phenotypes in malignant conditions, making it a potential target for cancer therapies. Recent studies have highlighted the importance of CSPG5 in the tumor microenvironment, where it may influence cellular interactions and signaling pathways that promote tumor growth and metastasis. Researchers are focusing on the recombinant form of CSPG5 to better understand its structure-function relationship and to explore its potential as both a biomarker for cancer diagnosis and a target for therapeutic intervention. By generating and characterizing CSPG5 recombinant proteins, scientists aim to investigate its interactions with various cell types and its impact on tumor behavior. This research not only enhances our understanding of CSPG5's role in oncology but also opens avenues for developing novel treatments that could inhibit tumor growth by targeting CSPG5-mediated pathways. Overall, the study of CSPG5 recombinant proteins is critical for unraveling the complexities of tumor biology and for identifying new strategies in cancer therapy.
