关键信息
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基因名
GPR141
- 应用
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别名
GPR141; PGR13; Probable G-protein coupled receptor 141; G-protein coupled receptor PGR13
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q7Z602
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表达区间
1-305aa
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氨基酸序列
MPGHNTSRNSSCDPIVTPHLISLYFIVLIGGLVGVISILFLLVKMNTRSVTTMAVINLVVVHSVFLLTVPFRLTYLIKKTWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKLHAVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIINYMIVIFVIAVAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFIGVILVCFLPYQFFRIYYLNVVTHSNACNSKVAFYNEIFLSVTAISCYDLLLFVFGGSHWFKQKIIGLWNCVLCR
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分子量
35.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
GPR141 is a member of the G protein-coupled receptor (GPCR) family, which plays a crucial role in various physiological processes and has emerged as a significant target in drug discovery. Initially identified through genomic studies, GPR141 has been linked to several critical functions, including regulation of metabolic pathways and signaling in the central nervous system. The exploration of GPR141's structure and function has gained momentum owing to its potential implications in metabolic disorders, psychiatric conditions, and cancer. Despite its importance, limited research has been conducted on the receptor, primarily due to challenges in obtaining sufficient amounts of functional protein for biochemical and biophysical studies. Recombinant protein technology has thus become a vital tool in GPR141 research, enabling the production of large quantities of the receptor for functional assays and structural analysis. This advancement is pivotal for elucidating the receptor's signaling mechanisms, interactions with ligands, and potential therapeutic applications. Understanding GPR141 at the molecular level could lead to the development of novel therapeutic strategies targeting this receptor, possibly resulting in innovative treatments for various diseases. Continued research is essential to uncover the full biological significance of GPR141 and its role in health and disease.
