关键信息
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基因名
GCG
- 应用
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别名
GCG；BOTCH;Glutathione-specific gamma-glutamylcyclotransferase 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P01275
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表达区间
53-89aa
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氨基酸序列
HSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIA
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分子量
6.4kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
The study of GCG (glucagon) recombinant proteins has gained significant attention due to their crucial role in glucose metabolism and potential therapeutic applications in diabetes management. Glucagon, a peptide hormone produced by the alpha cells of the pancreas, is essential for elevating blood glucose levels during hypoglycemic episodes. Advances in biotechnology have enabled the production of recombinant GCG proteins, which facilitate the study of its structure-function relationship, receptor interactions, and metabolic effects. The ability to generate high-purity GCG proteins is vital for both basic research and the development of novel glucose-regulating therapies. Understanding the mechanisms by which GCG influences insulin secretion and hepatic glucose production can lead to innovative strategies for treating metabolic disorders. Furthermore, recombinant GCG proteins offer opportunities for the design of biosimilars, potentially improving patient outcomes and access to therapies. As research progresses, insights gained from GCG recombinant proteins may revolutionize our approach to diabetes treatment and advance personalized medicine.
