关键信息
-
基因名
HECA
- 应用
-
别名
Gm869; HDC; HDC_HUMAN; HDCL; Headcase homolog (Drosophila); Headcase protein homolog; HECA; hHDC
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9UBI9
-
表达区间
1-543aa
-
氨基酸序列
MPNPKNSKGG RKNKRANSSG DEQENGAGAL AAAGAAGAAA GGALAAAAGC GAAAAGAPGA GGAAGAGGAG TGAANAAAAA GAAAAGDAKN EAPCATPLIC SFGRPVDLEK DDYQKVVCNN EHCPCSTWMH LQCFYEWESS ILVQFNCIGR ARSWNEKQCR QNMWTKKGYD LAFRFCSCRC GQGHLKKDTD WYQVKRMQDE KKKKSGSEKN TGRPPGEAAE EAKKCRPPNK PQKGPSHDLP RRHSMDRQNS QEKAVGAAAY GARSPGGSPG QSPPTGYSIL SPAHFSGPRS SRYLGEFLKN AIHLEPHKKA MAGGHVFRNA HFDYSPAGLA VHRGGHFDTP VQFLRRLDLS ELLTHIPRHK LNTFHVRMED DAQVGQGEDL RKFILAALSA SHRNVVNCAL CHRALPVFEQ FPLVDGTLFL SPSRHDEIEY DVPCHLQGRL MHLYAVCVDC LEGVHKIICI KCKSRWDGSW HQLGTMYTYD ILAASPCCQA RLNCKHCGKP VIDVRIGMQY FSEYSNVQQC PHCGNLDYHF VKPFSSFKVL EAY
-
分子量
58.8 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
HECA (Hematopoietic and Endothelial Cell Adhesion Molecule) is a member of the immunoglobulin superfamily and plays a crucial role in cell adhesion and signaling processes within the hematopoietic and endothelial systems. Research into HECA has surged due to its potential implications in various physiological and pathological conditions, including immune response, inflammation, and tumor metastasis. The expression and function of HECA are primarily observed in hematopoietic cells and vascular endothelial cells, making it a key factor in the interactions between blood cells and the vascular environment. Understanding the mechanisms of HECA, particularly in relation to its structural characteristics and binding affinities, can elucidate its role in mediating cell migration, trafficking, and adhesion. Additionally, dysregulation of HECA expression has been linked to various diseases, including autoimmune disorders and cancer, highlighting its potential as a therapeutic target. As researchers explore the structural and functional aspects of HECA, they aim to develop innovative strategies for modulating its activity, which could lead to novel treatments for diseases involving the hematopoietic and endothelial systems. This area of study not only enhances our understanding of cell biology but also paves the way for advancements in targeted therapies and drug development aimed at manipulating HECA interactions in disease contexts.
