关键信息
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基因名
HMX2
- 应用
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别名
HMX2; Homeobox protein HMX2; Homeobox protein H6 family member 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A2RU54
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表达区间
1-273aa
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氨基酸序列
MGSKEDAGKG CPAAGGVSSF TIQSILGGGP SEAPREPVGW PARKRSLSVS SEEEEPDDGW KAPACFCPDQ HGPKEQGPKH HPPIPFPCLG TPKGSGGSGP GGLERTPFLS PSHSDFKEEK ERLLPAGSPS PGSERPRDGG AERQAGAAKK KTRTVFSRSQ VYQLESTFDM KRYLSSSERA CLASSLQLTE TQVKTWFQNR RNKWKRQLSA ELEAANMAHA SAQTLVSMPL VFRDSSLLRV PVPRSLAFPA PLYYPGSNLS ALPLYNLYNK LDY
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分子量
29.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
HMX2 (Hemogen, also known as HEMGN) is a protein that plays a crucial role in heme biosynthesis and erythropoiesis, the process of red blood cell formation. Studies have demonstrated that HMX2 is involved in the regulation of hematopoietic stem cells and contributes to the differentiation of these cells into erythroid lineage. Understanding the function and mechanisms of HMX2 is particularly important in the context of various hematological disorders, such as anemia and other blood-related diseases. Research has shown that mutations or dysregulation of HMX2 can lead to impaired red blood cell production, emphasizing its potential as a therapeutic target. Additionally, the study of recombinant HMX2 protein allows researchers to explore its biochemical properties and interactions with other cellular components in a controlled environment, paving the way for potential applications in gene therapy and regenerative medicine. Given its pivotal role in the development and functioning of the hematopoietic system, HMX2 continues to garner attention in the fields of molecular biology and medicine, offering insights that could lead to innovative treatments for blood disorders and improved understanding of normal and pathological hematopoiesis.
