关键信息
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基因名
GPX7
- 应用
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别名
GPX7;GPX6;Glutathione peroxidase 7
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96SL4
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表达区间
20-187aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSHMQQEQD FYDFKAVNIR GKLVSLEKYR GSVSLVVNVA SECGFTDQHY RALQQLQRDL GPHHFNVLAF PCNQFGQQEP DSNKEIESFA RRTYSVSFPM FSKIAVTGTG AHPAFKYLAQ TSGKEPTWNF WKYLVAPDGK VVGAWDPTVS VEEVRPQITA LVRKLILLKR EDL
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分子量
22 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
GPX7, or Glutathione Peroxidase 7, is a member of the glutathione peroxidase family, which plays a crucial role in cellular defense against oxidative stress. Research into GPX7 has gained momentum due to its potential implications in various diseases, including cancer and neurodegenerative disorders. Many studies have demonstrated that GPX7 expression is regulated under different stress conditions and that its enzymatic activity is involved in the detoxification of reactive oxygen species (ROS). Interestingly, GPX7 has unique structural features that distinguish it from other members of the glutathione peroxidase family, making it a compelling target for understanding the molecular mechanisms of oxidative stress response. Furthermore, recent investigations suggest that GPX7 may also play a role in the regulation of signaling pathways associated with apoptosis and proliferation. Hence, the study of GPX7 recombinant proteins has become vital for elucidating its biological functions, exploring its therapeutic potential, and understanding its contribution to cellular homeostasis. By generating recombinant GPX7 proteins, researchers aim to investigate their functional properties, interactions with other cellular components, and their roles in disease progression, paving the way for novel therapeutic strategies aimed at modulating oxidative stress in various pathological contexts.
