关键信息
-
基因名
UBAC1
- 应用
-
别名
UBAC1；GBDR1；KPC2；UBADC1；Ubiquitin-associated domain-containing Protein 1
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9BSL1
-
表达区间
1-405aa
-
氨基酸序列
MFVQEEKIFAGKVLRLHICASDGAEWLEEATEDTSVEKLKERCLKHCAHGSLEDPKSITHHKLIHAASERVLSDARTILEENIQDQDVLLLIKKRAPSPLPKMADVSAEEKKKQDQKAPDKEAILRATANLPSYNMDRAAVQTNMRDFQTELRKILVSLIEVAQKLLALNPDAVELFKKANAMLDEDEDERVDEAALRQLTEMGFPENRATKALQLNHMSVPQAMEWLIEHAEDPTIDTPLPGQAPPEAEGATAAASEAAAGASATDEEARDELTEIFKKIRRKREFRADARAVISLMEMGFDEKEVIDALRVNNNQQNAACEWLLGDRKPSPEELDKGIDPDSPLFQAILDNPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQISRIFQTLNRT
-
分子量
72.3 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
UBAC1, or Ubiquitin-Binding Domain-containing Protein 1, plays a crucial role in regulating various cellular processes through its involvement in ubiquitination pathways. Ubiquitination, a post-translational modification, is essential for protein degradation, signaling, and cellular reorganization, making UBAC1 a vital component in maintaining cellular homeostasis. Recent studies have illuminated its significance in various biological processes, including immune responses, cancer progression, and neurodegenerative diseases, suggesting that dysregulation of UBAC1 may contribute to the pathophysiology of these conditions. The recombinant expression of UBAC1 has enabled researchers to explore its molecular interactions and functional characteristics in greater depth. By studying the structure and activity of UBAC1 through recombinant protein techniques, scientists aim to elucidate its mechanism of action and interactions with other ubiquitin-related proteins. This research not only enhances our understanding of the ubiquitin-proteasome system but also opens avenues for potential therapeutic interventions targeting UBAC1 in disease contexts. Overall, the investigation of UBAC1 recombinant protein is pivotal for advancing knowledge in cell biology and developing novel strategies for treating diseases characterized by impaired ubiquitination.
