关键信息
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基因名
KIAA0427
- 应用
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别名
CTIF; KIAA0427; CBP80/20-dependent translation initiation factor
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O43310
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表达区间
1-598aa
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氨基酸序列
MENSSAASASSEAGSSRSQEIEELERFIDSYVLEYQVQGLLADKTEGDGESERTQSHISQWTADCSEPLDSSCSFSRGRAPPQQNGSKDNSLDMLGTDIWAANTFDSFSGATWDLQPEKLDFTQFHRKVRHTPKQPLPHIDREGCGKGKLEDGDGINLNDIEKVLPAWQGYHPMPHEVEIAHTKKLFRRRRNDRRRQQRPPGGNKPQQHGDHQPGSAKHNRDHQKSYQGGSAPHPSGRPTHHGYSQNRRWHHGNMKHPPGDKGEAGAHRNAKETMTIENPKLEDTAGDTGHSSLEAPRSPDTLAPVASERLPPQQSGGPEVETKRKDSILPERIGERPKITLLQSSKDRLRRRLKEKDEVAVETTTPQQNKMDKLIEILNSMRNNSSDVDTKLTTFMEEAQNSTNSEEMLGEIVRTIYQKAVSDRSFAFTAAKLCDKMALFMVEGTKFRSLLLNMLQKDFTVREELQQQDVERWLGFITFLCEVFGTMRSSTGEPFRVLVCPIYTCLRELLQSQDVKEDAVLCCSMELQSTGRLLEEQLPEMMTELLASARDKMLCPSESMLTRSLLLEVIELHANSWNPLTPPITQYYNRTIQKLTA
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分子量
94 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
KIAA0427, also known as C10orf107, is a gene located on chromosome 10 that encodes a protein implicated in various cellular processes, though its exact function remains largely unexplored. Initial studies have indicated a potential role in cell proliferation and apoptosis, suggesting its involvement in cancer biology. Furthermore, KIAA0427 has been identified as a novel biomarker in certain types of cancer, which has sparked interest in its potential therapeutic applications. Recent advancements in molecular biology techniques, such as recombinant DNA technology, have facilitated the production of KIAA0427 recombinant proteins, allowing researchers to study their structural and functional properties in more detail. Understanding the biological roles of KIAA0427 through recombinant protein studies could unveil new insights into its mechanisms in cellular signaling and contribute to the development of targeted therapies. Moreover, elucidating the interactions of KIAA0427 with other molecular partners could provide a more comprehensive view of its impact on cancer progression and other diseases. As research progresses, the characterization of KIAA0427 recombinant proteins may play a crucial role in translational medicine, potentially leading to novel diagnostics and treatment strategies.
