关键信息
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基因名
STRA6
- 应用
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别名
STRA6；Receptor for retinol uptake STRA6
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BX79
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表达区间
1-50aa
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氨基酸序列
MSSQPAGNQTSPGATEDYSYGSWYIDEPQGGEELQPEGEVPSCHTSIPPG
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分子量
33.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
STRA6 (Stimulated by Retinoic Acid 6) is a membrane-associated receptor primarily known for its role in retinol uptake and transport in cells. Research into STRA6 has gained significant attention due to its implications in various physiological processes and diseases. STRA6 functions as a receptor for retinol-binding protein (RBP), facilitating the delivery of retinol, a vitamin A derivative crucial for vision, cellular differentiation, and immune function. Abnormal STRA6 expression has been linked to several developmental disorders, particularly those affecting retinal development and function, such as retinitis pigmentosa. In addition, STRA6 is implicated in conditions like diabetes and certain cancers, where dysregulated retinol metabolism may contribute to disease progression. The recombinant expression and characterization of STRA6 protein enable researchers to explore its structure-function relationship, binding affinities, and potential as a therapeutic target. Understanding STRA6's mechanisms can illuminate new strategies for addressing vitamin A deficiency and its related health issues, making it a focus of ongoing biomedical research.
