关键信息
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基因名
MAPRE3
- 应用
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别名
MAPRE3;Microtubule-associated Protein RP/EB family member 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15691
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表达区间
1-281aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MAVNVYSTSV TSENLSRHDM LAWVNDSLHL NYTKIEQLCS GAAYCQFMDM LFPGCVHLRK VKFQAKLEHE YIHNFKVLQA AFKKMGVDKI IPVEKLVKGK FQDNFEFIQW FKKFFDANYD GKDYNPLLAR QGQDVAPPPN PGDQIFNKSK KLIGTAVPQR TSPTGPKNMQ TSGRLSNVAP PCILRKNPPS ARNGGHETDA QILELNQQLV DLKLTVDGLE KERDFYFSKL RDIELICQEH ESENSPVISG IIGILYATEE GFAPPEDDEI EEHQQEDQDE Y
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分子量
34 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MAPRE3, or Microtubule Associated Protein Regulate 3, is a member of the MAPRE family that plays a vital role in microtubule dynamics and cellular processes such as mitosis and intracellular transport. Research into MAPRE3 has gained considerable attention due to its potential implications in cancer biology and neurodegenerative diseases. Recent studies suggest that MAPRE3 not only stabilizes microtubules but also participates in signaling pathways that regulate cell growth and survival. Aberrant expression of MAPRE3 has been associated with various malignancies, indicating its role as a possible oncogenic factor. Furthermore, the exploration of MAPRE3 as a therapeutic target is promising, as modulating its activity could lead to new strategies for treating cancer and neurodegenerative conditions. The recombinant protein form of MAPRE3 is indispensable for investigating its biochemical properties, interactions with other cellular proteins, and its functional implications in disease. Understanding the molecular mechanisms involving MAPRE3 is crucial for revealing its biological significance and potential as a drug target. A detailed characterization of MAPRE3 and its interactions may unveil new insights into microtubule-associated processes and pave the way for novel therapeutic approaches.
