关键信息
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基因名
KRTAP19-1
- 应用
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别名
KRTAP19-1; KAP19.1; KRTAP19.1; Keratin-associated protein 19-1; High tyrosine-glycine keratin-associated protein 19.1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IUB9
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表达区间
1-90aa
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氨基酸序列
MSHYGSYYGGLGYSCGGFGGLGYGYGCGCGSFCRRGSGCGYGGYGYGSGFGSYGYGSGFGGYGYGSGFGGYGYGCCRPSYNGGYGFSGFY
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分子量
9.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
KRTAP19-1, a member of the keratin-associated protein (KAP) family, has garnered significant interest in the field of molecular biology and dermatological research due to its role in skin and hair follicle biology. These proteins are primarily expressed in the outer root sheath of hair follicles and are believed to contribute to the structural integrity and mechanical properties of hair. Understanding the functionality and interactions of KRTAP19-1 is crucial, as mutations or dysregulation in KAPs can lead to a variety of hair disorders and skin conditions. Recent studies have highlighted its potential involvement in the differentiation of keratinocytes and its contribution to the formation of the hair shaft, underscoring its importance in maintaining healthy hair growth cycles. Furthermore, the recombinant production of KRTAP19-1 allows for detailed examination of its biochemical properties and potential applications in therapeutic strategies for hair loss and skin repair. By studying the structure-function relations of KRTAP19-1, researchers aim to uncover its roles in cellular signaling pathways, protein interactions, and tissue architecture, paving the way for advancements in dermatological treatments and regenerative medicine.
