关键信息
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基因名
MFAP3
- 应用
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别名
MFAP3;Microfibril-associated glycoProtein 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P55082
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表达区间
19-147aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSAFVLEDV DFDQMVSLEA NRSSYNASFP SSFELSASSH SDDDVIIAKE GTSVSIECLL TASHYEDVHW HNSKGQQLDG RSRGGKWLVS DNFLNITNVA FDDRGLYTCF VTSPIRASYS VTLRVIFTSG DM
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分子量
17 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MFAP3 (Microfibril Associated Protein 3) is a member of the microfibril-associated protein family, which plays a crucial role in extracellular matrix organization and cellular processes. Its expression is prominently noted in various tissues, particularly in connective tissues, suggesting a significant role in tissue development and repair. Recent studies have indicated that MFAP3 is involved in pathological processes, including fibrosis and cardiovascular diseases, highlighting its potential as a biomarker for these conditions. The interest in MFAP3 has grown due to its involvement in tumorigenesis and metastasis, where it may influence the tumor microenvironment and modulate cell adhesion, migration, and proliferation. Researchers are increasingly focused on developing recombinant MFAP3 proteins to elucidate their structural and functional properties, aiming to understand their role in cellular mechanisms and disease states. Utilizing advanced techniques such as recombinant DNA technology and protein purification methods, scientists are investigating the biochemical interactions and signaling pathways associated with MFAP3. This research could pave the way for novel therapeutic strategies targeting MFAP3 in diseases linked to the extracellular matrix, further underscoring its importance in both basic biology and clinical applications.
