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Rabbit Polyclonal SLC30A9 Antibody

  • 中文名: SLC30A9抗体
  • 别    名: Zinc transporter 9ZnT-9; Solute carrier family 30 member 9; Human embryonic lung protein; HUEL SLC30A9;
货号: IPDX42675
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesZinc transporter 9ZnT-9; Solute carrier family 30 member 9; Human embryonic lung protein; HUEL SLC30A9;
Entrez GeneID10463;
WB Predicted band size63kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthesized peptide derived from internal of human SLC30A9.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

以下是3篇关于SLC30A9抗体的参考文献概览(文献年份及摘要内容为模拟数据,实际引用请核实原文):

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1. **文献名称**: "SLC30A9 mediates vesicular zinc storage in neuronal cells"

**作者**: Smith JL, et al.

**摘要**: 本研究利用特异性SLC30A9抗体揭示了该蛋白在小鼠海马神经元突触囊泡中的定位,证实其通过调控锌离子稳态影响神经递质释放,为神经退行性疾病研究提供新靶点。

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2. **文献名称**: "SLC30A9 antibody validation in breast cancer cell lines"

**作者**: Chen R, Wang M.

**摘要**: 通过Western blot和免疫荧光验证SLC30A9抗体的特异性,发现该蛋白在乳腺癌细胞中高表达且与化疗耐药相关,提示其可能作为肿瘤标志物。

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3. **文献名称**: "Role of SLC30A9 in pancreatic β-cell function"

**作者**: Tanaka K, et al.

**摘要**: 使用SLC30A9敲除小鼠模型及抗体检测,证明该蛋白通过维持胰岛β细胞锌离子平衡调控胰岛素分泌,缺失导致糖代谢异常。

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*注:以上为模拟文献,实际研究请通过PubMed或Web of Science以关键词"SLC30A9 antibody"检索最新论文。建议优先选择近五年内发表且抗体验证数据完整(如KO验证、应用平台注明)的文献。*

背景信息

The SLC30A9 antibody is a tool used to detect and study the SLC30A9 protein, a member of the solute carrier family 30 (SLC30A), which regulates zinc transport and homeostasis in cells. SLC30A9. also known as ZnT9. functions as a zinc transporter, facilitating the movement of zinc ions across cellular membranes, particularly within organelles like the Golgi apparatus. This protein plays a critical role in maintaining intracellular zinc balance, which is essential for numerous biological processes, including enzyme function, signal transduction, and gene expression. Dysregulation of zinc transport has been linked to neurological disorders, metabolic diseases, and cancer.

The SLC30A9 antibody is widely used in research to investigate the protein's expression, localization, and interaction partners in various tissues, such as the brain, liver, and reproductive organs. It is commonly applied in techniques like Western blotting, immunohistochemistry, and immunofluorescence. Studies utilizing this antibody have contributed to understanding SLC30A9's involvement in developmental biology, neuroprotection, and its potential role in diseases like Alzheimer's and diabetes. Commercial SLC30A9 antibodies are typically raised in hosts like rabbits or mice, targeting specific epitopes of the protein. Validation methods, such as knockout controls or siRNA silencing, are crucial to confirm antibody specificity and reliability in experimental models.

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