关键信息
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基因名
LRCH4
- 应用
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别名
Leucine rich repeat neuronal 4; Leucine rich repeat neuronal protein 4; Leucine rich repeats and calponin homology (CH) domain containing 4; Leucine-rich neuronal protein; Leucine-rich repeat and calponin homology domain-containing protein 4; Leucine-rich repeat neuronal protein 4; Lrch4; LRCH4_HUMAN; LRN ; LRRN1 ; LRRN4 ; PP14183 ; SAP25 ; Sin3 associated polypeptide; 25kDa
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75427
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表达区间
1-683aa
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氨基酸序列
MAAAVAAPLAAGGEEAAATTSVPGSPGLPGRRSAERALEEAVATGTLNLSNRRLKHFPRGAARSYDLSDITQADLSRNRFPEVPEAACQLVSLEGLSLYHNCLRCLNPALGNLTALTYLNLSRNQLSLLPPYICQLPLRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTLPEELGDLPLVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPLQSPPAQVCLKGKLHIFKYLSTEAGQRGSALGDLAPSRPPSFSPCPAEDLFPGHRYDGGLDSGFHSVDSGSKRWSGNESTDEFSELSFRISELAREPRGPRERKEDGSADGDPVQIDFIDSHVPGEDEERGTVEEQRPPELSPGAGDRERAPSSRREEPAGEERRRPDTLQLWQERERRQQQQSGAWGAPRKDSLLKPGLRAVVGGAAAVSTQAMHNGSPKSSASQAGAAAGQGAPAPAPASQEPLPIAGPATAPAPRPLGSIQRPNSFLFRSSSQSGSGPSSPDSVLRPRRYPQVPDEKDLMTQLRQVLESRLQRPLPEDLAEALASGVILCQLANQLRPRSVPFIHVPSPAVPKLSALKARKNVESFLEACRKMGVPEADLCSPSDLLQGTARGLRTALEAVKRVGGKALPPLWPPSGLGGFVVFYVVLMLLLYVTYTRLLGS
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分子量
101.53 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
LRCH4, a member of the leucine-rich repeat (LRR) family, has gained attention in recent years due to its potential role in various biological processes and diseases. It is primarily known for its involvement in immune responses and cellular signaling pathways. Research indicates that LRCH4 may function as a key regulator of immune cell activation and differentiation, exerting both positive and negative regulatory effects depending on the context. Given its structural features, including multiple LRR domains, LRCH4 is hypothesized to interact with several protein partners, influencing a range of downstream signaling cascades. Investigating the recombinant form of LRCH4 has become crucial for understanding its biochemical properties and functional mechanisms. Studies utilizing recombinant LRCH4 aim to elucidate its role in autoimmune diseases, cancers, and infectious diseases, where dysregulation of immune signaling is often observed. By producing and characterizing LRCH4 as a recombinant protein, researchers aim to provide insights into its interactions, explore its therapeutic potential, and develop strategies for targeting LRCH4 in clinical settings. Overall, the study of LRCH4 recombinant protein represents a promising avenue for advancing our understanding of immunity and developing novel interventions for immune-related disorders.
