关键信息
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基因名
LRRC27
- 应用
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别名
LRRC27; KIAA1674; Leucine-rich repeat-containing protein 27
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9C0I9
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表达区间
1-530aa
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氨基酸序列
MEGSSSYEVP SVAAADLEEG AGQTRSLPAT PSKDVHKGVG GIIFSSSPIL DLSESGLCRL EEVFRIPSLQ QLHLQRNALC VIPQDFFQLL PNLTWLDLRY NRIKALPSGI GAHQHLKTLL LERNPIKMLP VELGSVTTLK ALNLRHCPLE FPPQLVVQKG LVAIQRFLRM WAVEHSLPRN PTSQEAPPVR EMTLRDLPSP GLELSGDHAS NQGAVNAQDP EGAVMKEKAS FLPPVEKPDL SELRKSADSS ENWPSEEEIR RFWKLRQEIV EHVKADVLGD QLLTRELPPN LKAALNIEKE LPKPRHVFRR KTASSRSILP DLLSPYQMAI RAKRLEESRA AALRELQEKQ ALMEQQRREK RALQEWRERA QRMRKRKEEL SKLLPPRRSM VASKIPSATD LIDNRKVPLN PPGKMKPSKE KSPQASKEMS ALQERNLEEK IKQHVLQMRE QRRFHGQAPL EEMRKAAEDL EIATELQDEV LKLKLGLTLN KDRRRAALTG NLSLGLPAAQ PQNTFFNTKY GESGNVRRYQ
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分子量
60 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
LRRC27 (Leucine-Rich Repeat Containing 27) is a gene encoding a protein involved in various cellular processes, including signal transduction and protein-protein interactions. Recent studies have highlighted its significance in several biological functions, particularly in the context of neuronal development and synaptic transmission. As a member of the leucine-rich repeat family, LRRC27 plays a crucial role in the assembly and maintenance of synapses, which are essential for effective communication between neurons. Aberrations in LRRC27 expression have been linked to neurological disorders, making it a potential target for therapeutic intervention. To better understand the functional mechanisms of LRRC27, researchers have focused on the production of recombinant LRRC27 protein, which allows for the investigation of its structure, interactions, and activity in vitro. This foundational research aims to elucidate its role in synaptic function and neurodevelopment, potentially unveiling new insights into its involvement in neurodegenerative diseases and offering avenues for novel treatments. Through the expression and characterization of LRRC27 recombinant protein, scientists aspire to bridge the knowledge gap surrounding this protein's contributions to neuronal health and disease.
