关键信息
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基因名
NUDT3
- 应用
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别名
NUDT3;DIPP;DIPP1;Diphosphoinositol polyphosphate phosphohydrolase 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95989
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表达区间
1-172aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MMKLKSNQTR TYDGDGYKKR AACLCFRSES EEEVLLVSSS RHPDRWIVPG GGMEPEEEPS VAAVREVCEE AGVKGTLGRL VGIFENQERK HRTYVYVLIV TEVLEDWEDS VNIGRKREWF KIEDAIKVLQ YHKPVQASYF ETLRQGYSAN NGTPVVATTY SVSAQSSMSG IR
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分子量
22 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
NUDT3 is a member of the Nudix hydrolase family, known for playing essential roles in cellular metabolism by hydrolyzing various nucleotides. Recent studies have highlighted the significance of NUDT3 in the regulation of cellular stress responses and the modulation of signaling pathways related to energy metabolism. NUDT3 has garnered attention for its potential implications in cancer biology, given its involvement in nucleotide homeostasis and the regulation of metabolic processes that are often dysregulated in cancer cells. Additionally, emerging evidence suggests that NUDT3 may influence the levels of pyrophosphate and other nucleotides, thereby affecting cellular signaling mechanisms and apoptosis. Understanding the biochemical properties and biological functions of NUDT3 could provide insights into its role in various diseases and present novel therapeutic targets. Researchers are actively investigating the structural and functional aspects of this enzyme to better appreciate its contributions to cellular health and disease mechanisms.
